发明名称 |
Multi-functional biocompatible coatings for intravascular devices |
摘要 |
A polymeric coating is adapted to substantially eliminate thrombus formation when in contact with blood. The polymeric coating includes a first polymeric layer and a second polymeric layer. Interposed between the first and second polymeric layers is a polymeric matrix layer doped with at least one of a nitric oxide donor and a nitric oxide generator. The nitric oxide donor and/or the nitric oxide generator are capable of releasing or generating NO. A bioactive agent is either immobilized to the surface of the second polymeric layer or is incorporated into the polymeric matrix layer. |
申请公布号 |
US2006039950(A1) |
申请公布日期 |
2006.02.23 |
申请号 |
US20040924102 |
申请日期 |
2004.08.23 |
申请人 |
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发明人 |
ZHOU ZHENGRONG;MEYERHOFF MARK E.;REYNOLDS MELISSA M. |
分类号 |
A61K31/727;A61F2/00;A61K31/655 |
主分类号 |
A61K31/727 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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