发明名称 Substituted cyclohexane derivatives.
摘要 The present invention provides compounds of formula (I) wherein A<SUP>1</SUP>, A<SUP>2</SUP>, A<SUP>3</SUP>, A<SUP>4</SUP>, A<SUP>5</SUP>, A<SUP>6</SUP>, A<SUP>7</SUP>, A<SUP>8</SUP>, A<SUP>9</SUP>, A<SUP>10</SUP>, U, V, W, m, n and p are as indicated in the specification, and pharmaceutically acceptable salts thereof. The compounds are useful for the treatment and/or prophylaxis of diseases which are associated with 2,3-oxidosqualene-lanosterol cyclase such as hypercholesterolemia and hyperlipemia.
申请公布号 ZA200404547(B) 申请公布日期 2006.02.22
申请号 ZA20040004547 申请日期 2004.06.08
申请人 F. HOFFMANN-LA ROCHE AG. 发明人 JEAN ACKERMANN;HENRIETTA DEHMLOW;HANS-PETER MAERKI;JOHANNES AEBI;GEORGES HIRTH;OLIVIER MORAND
分类号 C07D295/12;A61K31/18;A61K31/223;A61K31/27;A61K31/325;A61K31/397;A61K31/40;A61K31/4164;A61K31/445;A61K31/4453;A61K31/505;A61K31/5375;A61P1/16;A61P3/06;A61P3/10;A61P9/00;A61P9/10;A61P31/10;A61P33/00;A61P35/00;A61P43/00;C07B61/00;C07C269/04;C07C269/06;C07C271/46;C07C271/48;C07C271/52;C07C291/04;C07C303/40;C07C311/17;C07C311/18;C07D203/12;C07D205/04;C07D207/08;C07D211/46;C07D233/52;C07D233/60;C07D239/42;C07D295/084;C07D295/088;C07D295/10;C07D295/135;C07D521/00 主分类号 C07D295/12
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