发明名称 |
PHARMACEUTICAL COMPOSITION COMPRISING FGF18 AND IL-1 ANTAGONIST AND METHOD OF USE |
摘要 |
<p>FGF18 is known to stimulate the proliferation of chondrocytes, bone, and nervous tissue, resulting in repair of diseased tissue. When an IL-1 antagonist is administered in addition to FGF18, the effects on the IL-1 mediated disease and also, the effect on cartilage, bone, and nervous cell proliferation, are found to be greater than administration of FGF18 or the IL-1 antagonist alone. The present invention encompasses a pharmaceutical composition that combines FGF18 with IL-1 antagonist and methods of treating IL-1 mediated disease using this pharmaceutical composition.</p> |
申请公布号 |
WO2006014444(A1) |
申请公布日期 |
2006.02.09 |
申请号 |
WO2005US23866 |
申请日期 |
2005.07.06 |
申请人 |
ZYMOGENETICS, INC.;MOORE, EMMA, E.;ELLSWORTH, JEFF, L. |
发明人 |
MOORE, EMMA, E.;ELLSWORTH, JEFF, L. |
分类号 |
(IPC1-7):A61K38/18;A61K38/17;A61K39/395;A61P19/00;A61P11/00;A61P25/00;A61P29/00;A61P35/00;A61P9/00 |
主分类号 |
(IPC1-7):A61K38/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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