发明名称 ANTISENSE MODULATION OF SURVIVIN EXPRESSION
摘要 PROBLEM TO BE SOLVED: To obtain an antisense compound, a composition and to provide a method for modulating the expression of Survivin. SOLUTION: The composition comprises the antisense compound targeted to a nucleic acid encoding Survivin, particularly a pharmaceutical composition containing an antisense oligonucleotide and modulation of Survivin expression is provided, and methods for using the compounds and for treatment of diseases associated with the expression of Survivin are provided. COPYRIGHT: (C)2006,JPO&NCIPI
申请公布号 JP2006028188(A) 申请公布日期 2006.02.02
申请号 JP20050216823 申请日期 2005.07.27
申请人 ISIS PHARMACEUT INC 发明人 BENNETT C FRANK;ACKERMANN ELIZABETH J;SWAYZE ERIC E;COWSERT LEX M
分类号 A61K31/7088;C07H21/04;A61K9/10;A61K31/337;A61K31/711;A61K31/7115;A61K31/712;A61K31/7125;A61K33/24;A61K38/00;A61K45/00;A61K48/00;A61P29/00;A61P31/00;A61P35/00;A61P43/00;C07H21/00;C12N15/09;C12N15/113;C12P21/04 主分类号 A61K31/7088
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