发明名称 |
Novel irreversible inhibitors of epidermal growth factor receptor tyrosine kinase and uses thereof for therapy and diagnosis |
摘要 |
Novel epidermal growth factor receptor tyrosine kinase (EGFR-TK) irreversible inhibitors, pharmaceutical compositions including same and their use in the treatment of EGFR-TK related diseases or disorders are disclosed. Novel radiolabeled EGFR-TK irreversible inhibitors as their use as biomarkers for medicinal radioimaging such as Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT) and as radiopharmaceuticals for radiotherapy are further disclosed.
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申请公布号 |
US2006025430(A1) |
申请公布日期 |
2006.02.02 |
申请号 |
US20050185698 |
申请日期 |
2005.07.21 |
申请人 |
MISHANI EYAL;ROZEN YULIA;ABOURBEH GALITH;LEVITZKI ALEXANDER |
发明人 |
MISHANI EYAL;ROZEN YULIA;ABOURBEH GALITH;LEVITZKI ALEXANDER |
分类号 |
A61K31/517;A61K;C07D239/84;C07D239/88;C07D239/93;C07D239/94 |
主分类号 |
A61K31/517 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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