发明名称 |
Controlled release of injected drugs which extends the duration of action of the drugs or the triggering of the immune response |
摘要 |
Described is a pharmaceutical composition and method for controlling the release of a drug or vaccine to a patient where a slow, controlled release of drug or antigen occurs over a considerable period of time after injection. The drug or vaccine is contained in sugar glass microspheres and then placed in an anhydrous liquid, preferably perfluorocarbon, so that the vaccine is protected against dissolution while remaining surrounded by anhydrous liquid. This simple non-toxic system, deliverable by current syringe or present or future needle-free systems, is inexpensive and reliable and aids in parenteral drug delivery or mass immunization campaigns by reducing the need for repeated injections. |
申请公布号 |
NZ527714(A) |
申请公布日期 |
2006.01.27 |
申请号 |
NZ20020527714 |
申请日期 |
2002.02.14 |
申请人 |
CAMBRIDGE BIOSTABILITY LTD |
发明人 |
ROSER, BRUCE JOSEPH;DE CASTRO, ARCADIO GARCIA |
分类号 |
A61K47/26;A61K9/00;A61K9/10;A61K9/16;A61K9/34;A61K9/36;A61K9/38;A61K9/50;A61K9/52;A61K9/58;A61K9/60;A61K9/62;A61K9/64;A61K9/66;A61K39/00;A61K47/02;A61K47/10;A61K47/12;(IPC1-7):A61K9/00 |
主分类号 |
A61K47/26 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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