FULLY HUMAN ANTIBODIES AGAINST HUMAN 4-1BB (CD137)
摘要
Fully human antibodies and antigen-binding portions thereof that bind to human 4-1BB and that allow binding of human 4-1BB to a human 4-1BB ligand. In one aspect, the antibody is an IgG4 antibody. Also provided is a method for treating a disease in a subject comprising administering a therapeutically effective amount of the antibody to said subject.
申请公布号
WO2005035584(A8)
申请公布日期
2006.01.26
申请号
WO2004US33587
申请日期
2004.10.12
申请人
BRISTOL-MYERS SQUIBB COMPANY;JURE-KUNKEL, MARIA;HEFTA, LAURA, J.;SANTORO, MARC;GANGULY, SUBINAY;HALK, EDWARD, L.
发明人
JURE-KUNKEL, MARIA;HEFTA, LAURA, J.;SANTORO, MARC;GANGULY, SUBINAY;HALK, EDWARD, L.