发明名称 |
CHAPERONINE-TARGET PROTEIN COMPLEX, METHOD OF PRODUCING THE SAME, METHOD OF STABILIZING TARGET PROTEIN, METHOD OF IMMOBILIZING TARGET PROTEIN, METHOD OF ANALYZING THE STRUCTURE OF TARGET PROTEIN, SUSTAINED-RELEASE PREPARATION AND METHOD OF PRODUCING ANTIBODY AGAINST TARGET PROTEIN |
摘要 |
<p>The present invention provides a chaperonin-target protein complex and a method of producing the same, and a method of stabilizing the target protein, a method of immobilizing the target protein, a method of analyzing the structure of the target protein, a sustained-release formulation, and a method of producing an antibody against the target protein. The chaperonin-target protein complex in the present invention includes a fusion protein having a chaperonin subunit and an affinity tag linked to the chaperonin subunit via a peptide bond and a target protein for which the affinity tag shows a specific affinity, wherein the target protein is bound to the affinity tag by means of the specific affinity, thereby forming a chaperonin ring structure consisting of a plurality of chaperonin subunits. The chaperonin-target protein in the present invention stabilizes the target protein and surely immobilize on a carrier without causing any change in its stereostructure.</p> |
申请公布号 |
EP1619208(A1) |
申请公布日期 |
2006.01.25 |
申请号 |
EP20040730054 |
申请日期 |
2004.04.28 |
申请人 |
SEKISUI CHEMICAL CO., LTD. |
发明人 |
IDENO, AKIRA;HATA, JUN-ICHI;TOGI, AKIKO;FURUTANI, MASAHIRO |
分类号 |
A61K38/17;C12N15/62;C12P21/08;G01N33/68;(IPC1-7):C07K19/00;A61K38/16;C12P21/02;G01N33/48;G01N33/566 |
主分类号 |
A61K38/17 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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