发明名称 |
METHOD AND SYSTEM FOR SYSTEMIC DELIVERY OF GROWTH ARRESTING, LIPID-DERIVED BIOACTIVE COMPOUNDS |
摘要 |
<p>A system and method for optimizing the systemic delivery of growth-arresting lipid-derived bioactive drugs or gene therapy agents to an animal or human in need of such agents utilizing nanoscale assembly systems, such as liposomes, resorbable and non-aggregating nanoparticle dispersions, metal or semiconductor nanoparticles, or polymeric materials such as dendrimers or hydrogels, each of which exhibit improved lipid solubility, cell permeability, an increased circulation half life and pharmacokinetic profile with improved tumor or vascular targeting.</p> |
申请公布号 |
EP1617808(A2) |
申请公布日期 |
2006.01.25 |
申请号 |
EP20040760381 |
申请日期 |
2004.04.26 |
申请人 |
THE PENN STATE RESEARCH FOUNDATION |
发明人 |
KESTER, MARK;STOVER, THOMAS;LOWE, TAO;ADAIR, JAMES;KIM, YOUNG, SHIN |
分类号 |
A61K9/127;A61K;A61K9/16;A61K48/00;C12N15/88;(IPC1-7):A61K6/00 |
主分类号 |
A61K9/127 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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