| 发明名称 |
PYRIDAZINONE DERIVATIVES AND THEIR USE AS INHIBITORS OF PROSTAGLANDIN G/H SYNTHASE I AND II(COX I AND II) |
| 摘要 |
Compounds of formula I: (see formula I) where: R10 is a group represented by formula (A), (B), or (C): (see formula A, B, C) and the other substituents are as defined in the specification; and their pharmaceutically acceptable salts are inhibitors of prostaglandin G/H synthase and are anti-inflammatory and analgesic agents.
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| 申请公布号 |
CA2205757(C) |
申请公布日期 |
2006.01.24 |
| 申请号 |
CA19972205757 |
申请日期 |
1997.05.21 |
| 申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
ALLEN, DARIN ARTHUR;SJOGREN, ERIC BRIAN;DUNN, JAMES PATRICK;SMITH, DAVID BERNARD |
| 分类号 |
C07D409/10;A61K31/50;A61K31/501;A61P25/04;A61P29/00;C07D237/04;C07D237/14;C07D401/10;C07D405/10 |
主分类号 |
C07D409/10 |
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