| 发明名称 |
SUBSTITUTED 1,4-DIAZEPINES AND USES THEREOF |
| 摘要 |
The present invention is directed to novel 1,4-diazepines, pharmaceutical compositions thereof, and the use thereof as inhibitors of HDM2-p53 interactions. Compounds have Formula I as defined herein, with R 1 to R 8 and X as defined herein or a solvate, hydrate or pharmaceutically acceptable salt thereof.
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| 申请公布号 |
KR20060007035(A) |
申请公布日期 |
2006.01.23 |
| 申请号 |
KR20057020301 |
申请日期 |
2005.10.25 |
| 申请人 |
ORTHO-MCNEIL PHARMACEUTICAL, INC. |
发明人 |
LU TIANBAO;MILKIEWICZ KAREN L.;RABOISSON PIERRE;CUMMINGS MAXWELL DAVID;CALVO RAUL R.;PARKS DANIEL J.;LAFRANCE LOUIS V. III;MARUGAN SANCHEZ JUAN JOSE;GUSHUE JOAN;LEONARD KRISTI |
| 分类号 |
C07D243/14;A61K;C07D405/06;H04L12/56 |
主分类号 |
C07D243/14 |
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