发明名称 |
Heterocyclo inhibitors of potassium channel function |
摘要 |
Novel heterocyclo compounds useful as inhibitors of potassium channel function (especially inhibitors of the K<SUB>v</SUB>1 subfamily of voltage gated K<SUP>+</SUP> channels, especially inhibitors K<SUB>v</SUB>1.5 which has been linked to the ultra-rapidly activating delayed rectifier K<SUP>+</SUP> current I<SUB>Kur</SUB>), methods of using such compounds in the prevention and treatment of arrhythmia and I<SUB>Kur</SUB>-associated conditions, and pharmaceutical compositions containing such compounds.
|
申请公布号 |
US2006014792(A1) |
申请公布日期 |
2006.01.19 |
申请号 |
US20050186991 |
申请日期 |
2005.07.21 |
申请人 |
LLOYD JOHN;JEON YOON T;FINLAY HEATHER;YAN LIN;GROSS MICHAEL F;BEAUDOIN SERGE |
发明人 |
LLOYD JOHN;JEON YOON T.;FINLAY HEATHER;YAN LIN;GROSS MICHAEL F.;BEAUDOIN SERGE |
分类号 |
C07D211/26;C07D233/04;A61K31/445;A61K31/4535;A61K31/454;A61K31/4545;A61K31/496;A61K31/497;A61K31/506;A61K31/5377;A61K31/55;A61P1/04;A61P3/10;A61P9/00;A61P9/06;A61P11/08;A61P25/06;A61P25/08;A61P25/28;A61P29/00;A61P37/00;A61P43/00;C07D211/28;C07D211/34;C07D211/58;C07D211/62;C07D211/64;C07D211/96;C07D223/04;C07D401/04;C07D401/06;C07D401/12;C07D401/14;C07D403/12;C07D405/04;C07D405/12;C07D409/04;C07D409/12;C07D409/14;C07D413/04;C07D413/06;C07D413/12;C07D413/14;C07D417/06;C07D417/12;C07D521/00 |
主分类号 |
C07D211/26 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|