发明名称 |
Sensitivity test to predict efficacy of anti-cancer therapies |
摘要 |
The present disclosure provides methods for determining the sensitivity of cancerous cells to various anti-cancer therapies and predicting the efficacy of these therapies. Specifically, the present disclosure provides methods for predicting the efficacy of one or more candidate anti-cancer therapies in a patient, based on determining the sensitivity of the patient's cancerous cells after exposure to candidate anti-cancer therapies in vitro. The disclosure further provides methods for predicting the efficacy of candidate anti-cancer therapies by using an in vitro sensitivity test of the patient's cancerous cells and a surrogate in vivo efficacy test of the patient's cancerous cells grafted into a surrogate host. The disclosure further provides methods for selecting the most efficacious anti-cancer therapy(s) for a patient, thereby avoiding ineffective or unnecessary treatments.
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申请公布号 |
US2006014157(A1) |
申请公布日期 |
2006.01.19 |
申请号 |
US20040913711 |
申请日期 |
2004.08.06 |
申请人 |
KAWABE TAKUMI;KOBAYASHI HIDETAKA |
发明人 |
KAWABE TAKUMI;KOBAYASHI HIDETAKA |
分类号 |
C12Q1/68;A61K31/4745;A61K33/24;A61K45/06;G01N33/50;G01N33/574 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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