USE OF A COMPOUND FOR ENHANCING THE EXPRESSION OF MEMBRANE PROTEINS ON THE CELL SURFACE
摘要
The present invention is directed to the use of a compound stimulating deubiquitinating activity in a cell for the manufacture of a medicament for enhancing the expression of integral membrane proteins on the cell surface. Especially, the invention is directed to the use of such compound for the manufacture of a medicament for the treatment of a disease of condition selected from the group consisting of cystic fibrosis, diabetes insipidus, hypercholesterinaemia and long QT-syndrome-2.
申请公布号
WO2006002453(A2)
申请公布日期
2006.01.12
申请号
WO2005AT00251
申请日期
2005.07.06
申请人
BRUNAR, HELMUT;FREISSMUTH, MICHAEL;KIRPEMKO, TETYANA;NANOFF, CHRISTIAN;KORKHOV, VOLODYMR, M.
发明人
FREISSMUTH, MICHAEL;KIRPEMKO, TETYANA;NANOFF, CHRISTIAN;KORKHOV, VOLODYMR, M.