发明名称 USE OF A COMPOUND FOR ENHANCING THE EXPRESSION OF MEMBRANE PROTEINS ON THE CELL SURFACE
摘要 The present invention is directed to the use of a compound stimulating deubiquitinating activity in a cell for the manufacture of a medicament for enhancing the expression of integral membrane proteins on the cell surface. Especially, the invention is directed to the use of such compound for the manufacture of a medicament for the treatment of a disease of condition selected from the group consisting of cystic fibrosis, diabetes insipidus, hypercholesterinaemia and long QT-syndrome-2.
申请公布号 WO2006002453(A2) 申请公布日期 2006.01.12
申请号 WO2005AT00251 申请日期 2005.07.06
申请人 BRUNAR, HELMUT;FREISSMUTH, MICHAEL;KIRPEMKO, TETYANA;NANOFF, CHRISTIAN;KORKHOV, VOLODYMR, M. 发明人 FREISSMUTH, MICHAEL;KIRPEMKO, TETYANA;NANOFF, CHRISTIAN;KORKHOV, VOLODYMR, M.
分类号 A61K38/16;A61P3/06;A61P9/06;A61P11/00;A61P43/00;C12N15/63 主分类号 A61K38/16
代理机构 代理人
主权项
地址