LEVALBUTEROL HYDROCHLORIDE POLYMORPH A

摘要

The invention is directed to processes for making levalbuterol HC1 Polymorph A from by suspending or forming a first slurry of (R)-SLB(D)-DBTA in at least a first organic solvent, adding HC1 to the suspension or slurry of the solid (R)-SLB.D-DBTA until the (R)-SLB.D-DBTA forms levalbuterol HC1 Polymorph A, and isolating the levalbuterol HC1 Polymorph A.