发明名称 Peptide antagonists of prostaglandin F2alpha receptor
摘要 The present invention relates to a new class of G protein-coupled receptor agonist or antagonist, which specifically binds to the receptor protein structural elements, thus altering signal transmission and subsequent physiological effects. Described herein are peptide sequences derived from the G protein-coupled receptor protein, produced by chemical methods as selective inhibitors of signal transduction associated with stimulation of the receptor by its ligand. Such peptides or molecules derived from their primary, secondary or tertiary structures may be used as effective tocolytics for the prevention of premature labor or be used for the treatment of dysmenorrhea.
申请公布号 US6984719(B1) 申请公布日期 2006.01.10
申请号 US20010787334 申请日期 2001.06.19
申请人 HOSPITAL SAINTE-JUSTINE 发明人 CHEMTOB SYLVAIN;PERI KRISHNA G.
分类号 A61K38/04;A01N37/18;A61K38/00;C07K14/00;C07K16/00 主分类号 A61K38/04
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