| 发明名称 |
Inhibitors of akt activity |
| 摘要 |
The present invention is directed to compounds which contain a five-membered heterocyclic ring fused to a substituted pyrazine moiety which inhibit the activity of Akt, a serine/threonine protein kinase. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for treating cancer comprising administration of the compounds of the invention.
|
| 申请公布号 |
US2005288294(A1) |
申请公布日期 |
2005.12.29 |
| 申请号 |
US20050530252 |
申请日期 |
2005.04.05 |
| 申请人 |
DUGGAN MARK E;LINDSLEY CRAIG W;ZHAO ZHIJIAN |
发明人 |
DUGGAN MARK E.;LINDSLEY CRAIG W.;ZHAO ZHIJIAN |
| 分类号 |
A61K31/495;A61K31/498;A61K45/06;C07D241/36;C07D487/02;C07D487/04;C07D495/04;C07D519/00;(IPC1-7):A61K31/498 |
主分类号 |
A61K31/495 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
