摘要 |
The invention relates to compositions, such as pharmaceuticals, foods, food additives, or dietary supplements, containing dimer digallates, and methods of use thereof, for prophylactic or therapeutic treatment of a human or a veterinary animal to treat or prevent NO-responsive health conditions, treat hypertension, cardiovascular disease, coronary artery disease, diabetes, cognitive dysfunction or disorder and/or vascular circulation disorders, prevent or reduce the risk of heart attack, stroke, congestive heart failure and/or kidney failure, or to improve blood flow, for example renal blood flow. The composition may optionally contain an additional NO modulating agent and/or a vascular-protective or therapeutic agent, or may be administered in combination with such an agent. |
申请人 |
MARS, INCORPORATED |
发明人 |
SCHMITZ, HAROLD, H.;KWIK-URIBE, CATHERINE;KELM, MARK, A.;HAMMERSTONE, JOHN, F., JR.;ROMANCZYK, LEO, J., JR. |