发明名称 |
ARZNEIMITTELABGABE AUS STENTS |
摘要 |
An intravascular stent has a coat comprising a crosslinked amphiphilic polymer and a sparingly water soluble matrix metalloproteinase inhibitor (MMPI). Preferably the polymer is formed from 2-methacryloyloxy-2′-ethyltrimethylammonium phosphate inner salt, C4-18 alkyl methacrylate and reactive and/or crosslinking monomer and the MMPI is a hydroxamic acid, more preferably batimastat. Preclinical and clinical results are reported, showing good luminal areas and reduced intimal thickening. |
申请公布号 |
DE60207379(D1) |
申请公布日期 |
2005.12.22 |
申请号 |
DE2002607379 |
申请日期 |
2002.01.11 |
申请人 |
ABBOTT LABORATORIES, ABBOTT PARK |
发明人 |
LEWIS, ANDREW LENNARD;STRATFORD, PETER WILLIAM;DRIVER, MICHAEL JOHN |
分类号 |
A61L31/00;A61F2/84;A61K31/16;A61K31/381;A61L29/00;A61L31/10;A61L31/16;A61L33/00;A61P9/10;A61P43/00;(IPC1-7):A61L31/10 |
主分类号 |
A61L31/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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