摘要 |
<p>Disclosed is a method for treating the symptoms of an acute or chronic disorder mediated by the classical pathway of the complement cascade, comprising administering to a mammal in need of such treatment a therapeutically effective amount of a compound of Formula I or a solvate, hydrate or pharmaceutically acceptable salt thereof; wherein R<SUP>1</SUP>, R<SUP>2</SUP>, R<SUP>3</SUP>, R<SUP>4 </SUP>and R<SUP>7 </SUP>are defined in the specification, Z is SO or SO<SUB>2</SUB>, and Ar is an aromatic or heteroaromatic group as defined herein.</p> |