TRANSDERMAL TULOBUTEROL DELIVERY

摘要

A transdermal tulobuterol delivery system, preferably in the form of a single-layer, drug-in-adhesive matrix patch, is disclosed comprising a relatively low, (less than five weight percent) concentration of tulobuterol base dissolved in a skin adhesive composition containing at least one skin permeation enhancer. The transdermal delivery system of this invention provides controlled release of the active ingredient, includes a relatively low concentration of tulobuterol within the skin-contacting adhesive formulation of a transdermal patch, and provides acceptable sustained transdermal delivery of the dissolved tulobuterol, as well as acceptable tack and. peel adhesive properties for the delivery device.