发明名称 |
Compounds having affinity for the granulocyte-colony stimulating factor receptor (G-CSFR) and associated uses |
摘要 |
Novel compounds are provided that bind to G-CSFR. The novel compounds have a peptide chain approximately 6 to 40 amino acids in length that binds to G-CSFR. The compounds are useful as probes for affinity screening. In addition, the compounds have demonstrated agonist or antagonist activity for the G-CSFR, and are therefore useful in treatment of diseases including patients who suffer from a low white blood cell titer. Pharmaceutical compositions and methods of use are provided as well.
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申请公布号 |
US2005277588(A1) |
申请公布日期 |
2005.12.15 |
申请号 |
US20040929988 |
申请日期 |
2004.08.30 |
申请人 |
CWIRLA STEVEN E;BALU PALANI;DUFFIN DAVID J;PIPLANI SUNILA;MCEOWEN MERRILL BARBARA;SCHATZ PETER J |
发明人 |
CWIRLA STEVEN E.;BALU PALANI;DUFFIN DAVID J.;PIPLANI SUNILA;MCEOWEN MERRILL BARBARA;SCHATZ PETER J. |
分类号 |
A61K38/00;A61K38/08;A61K38/10;C07K7/06;C07K7/08;C07K14/53;C07K14/535;(IPC1-7):A61K38/10 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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