| 摘要 |
It is intended to provide a composition containing beta-glucan in which the physiologically active effects of beta-1,3-1,6-glucan contained in the culture medium of a bacterium belonging to the genus Aureobacidium sp. are further enhanced, and a constipation-relieving drug, an immunopontentiator and a skin moistening agent using the composition. A composition containing beta-glucan, which contains a culture medium containing beta-1,3-1,6-glucan obtained by culturing a bacterium belonging to the genusAureobacidium sp. together with lactic acid bacterium cells, is obtained. This composition containing beta-glucan is employed as the active ingredient of a constipation- relieving drug, an immunopontentiator and a skin moistening agent. As the above-described bacterium belonging to the genus Aureobacidium sp., Aureobasidium pullulans M-1 (FERM BP-08615) is preferable. As the above-described lactic acid bacterium, Enterococcus faecalis is preferable. It is still preferable that this lactic acid bacterium has been killed by heating. The content of the culture medium in solid matters preferably ranges from 1 to 80% by mass in terms of beta-1,3-1, 6-glucan, while the content of the lactic acid bacterium cells preferably ranges from 4 to 95% by mass.
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