摘要 |
<p>A compound highly active in, e.g., the inhibition of tyrosinase activity which is of the same class as shogaol and zingerol, which are useful in the fields of foods, medicines, quasi- drug preparations, cosmetics, etc. It is a compound represented by the following general formula (1): (1) wherein R1 is hydrogen, lower alkyl, or a protective group; R2 is hydrogen or a protective group; A and B each is alkylene; R3 is -COOR4 (R 4 is a protective group), carboxy, or -CH2OH; Z is -CO- CH=CH-, -CHOH-CH=CH-, -CHOH-1,2-epoxy-, -CO-CH2CH2-, - CHOH-CH2CH2-, -CO-CH2CHOH-, -CHOH-CH2 CHOH-, -CO-CH2CHOR5-, -CHOH-CH2CHOR5-, a ketal derivative of -CO-CH=CH-, or a ketal derivative of -CO-CH 2CH2-; and R5 is lower alkyl.</p> |