发明名称 |
Process for the production of opiates |
摘要 |
A morphine component, e.g., a concentrate of poppy straw, is converted into codeine in high yield and high purity and in a highly controlled manner. The conversion process involves the following steps: (a) providing a solution or suspension of a morphine component in an inert solvent or a mixture of solvents; (b) methylating the resultant solution or suspension with a methylating agent in the presence of an alkaline ingredient; and (c) recovering the resultant codeine as the free base or as a salt.
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申请公布号 |
US6972332(B1) |
申请公布日期 |
2005.12.06 |
申请号 |
US20040850015 |
申请日期 |
2004.05.20 |
申请人 |
ACURA PHARMACEUTICALS, INC. |
发明人 |
FRANCIS CHARLES A. |
分类号 |
C07D489/00;C07D489/02;(IPC1-7):C07D489/02 |
主分类号 |
C07D489/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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