发明名称 Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds
摘要 Disclosed are compounds which inhibit beta-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions that include a compound which inhibits beta-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.
申请公布号 US2005267150(A1) 申请公布日期 2005.12.01
申请号 US20040002921 申请日期 2004.12.03
申请人 THOMPSON RICHARD C;WILKIE STEPHEN;STACK DOUGLAS R;VANMETER ELDON E;SHI QING;BRITTON THOMAS C;AUDIA JAMES E;REEL JON K;MABRY THOMAS E;DRESSMAN BRUCE A;CWI CYNTHIA L;HENRY STEVEN S;MCDANIEL STACEY L;STUCKY RUSSELL D;PORTER WARREN J 发明人 THOMPSON RICHARD C.;WILKIE STEPHEN;STACK DOUGLAS R.;VANMETER ELDON E.;SHI QING;BRITTON THOMAS C.;AUDIA JAMES E.;REEL JON K.;MABRY THOMAS E.;DRESSMAN BRUCE A.;CWI CYNTHIA L.;HENRY STEVEN S.;MCDANIEL STACEY L.;STUCKY RUSSELL D.;PORTER WARREN J.
分类号 A61K31/445;A61K31/4706;A61K31/501;A61K31/55;A61K38/00;C07D401/12;C07D403/12;C07K5/097;(IPC1-7):A61K31/470 主分类号 A61K31/445
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