| 摘要 |
A drug for topically administration which is effective as an antiallergic agent. The drug for topically administration contains as an active ingredient an adenine compound represented by the general formula (1): <CHEM> Äwherein ring A represents a 6 to 10 membered, mono or bicyclic, aromatic hydrocarbon or a 5 to 10 membered, mono or bicyclic, aromatic heterocycle containing one to three heteroatoms selected among 0 to 2 nitrogen atoms, 0 or 1 oxygen atom, and 0 or 1 sulfur atom; n is an integer of 0 to 2; m is an integer of 0 to 2; R represents halogeno, (un)substituted alkyl, etc.; X<1> represents oxygen, sulfur, NR<1> (R<1> represents hydrogen or alkyl), or a single bond; Y<1> represents a single bond, alkylene; etc.; Y<2> represents a single bond, alkylene, etc.; Z represents alkylene; and at least one of Q<1> and Q<2> represents -COOR<10> (wherein R<10> represents (un)substituted alkyl, etc.), etc.Ü or a pharmaceutically acceptable salt of the compound. <IMAGE> |
