发明名称 |
Regulation of transcription with a cis-acting ribozyme |
摘要 |
The present invention provides a recombinant transcription unit capable of producing an RNA transcript of a predetermined size comprising a regulatory sequence operably linked to a nucleotide sequence comprising a transcribed region such that the transcription of said transcribed region is controlled by said regulatory sequence. The transcribed region comprises a region that encodes for a viral sequence, and a non-coding region downstream of the region encoding for said viral sequence, wherein the non-coding region comprises a nucleotide sequence encoding a cis-acting ribozyme. Methods of using the recombinant transcription unit, and cells containing vectors comprising the recombinant transcription unit are also disclosed.
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申请公布号 |
US2005257277(A1) |
申请公布日期 |
2005.11.17 |
申请号 |
US20040847728 |
申请日期 |
2004.05.17 |
申请人 |
LU XIAOBIN;DROPULIC BORO;SLEPUSHKIN VLADIMIR;BINDER GWENDOLYN |
发明人 |
LU XIAOBIN;DROPULIC BORO;SLEPUSHKIN VLADIMIR;BINDER GWENDOLYN |
分类号 |
A01K67/027;C12N15/11;C12N15/86;C12N15/867;(IPC1-7):A01K67/027 |
主分类号 |
A01K67/027 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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