发明名称 Methods of treating ankylosing spondylitis using anti-TNF antibodies and peptides of human tumor necrosis factor
摘要 Anti-TNF antibodies, fragments and regions thereof which are specific for human tumor necrosis factor-alpha (TNFalpha) and are useful in vivo diagnosis and therapy of a number of TNFalpha-mediated pathologies and conditions, including ankylosing spondylitis, as well as polynucleotides coding for murine and chimeric antibodies, methods of producing the antibody, methods of use of the anti-TNF antibody, or fragment, region or derivative thereof, in immunoassays and immunotherapeutic approaches are provided.
申请公布号 US2005249735(A1) 申请公布日期 2005.11.10
申请号 US20040010954 申请日期 2004.12.13
申请人 NEW YORK UNIVERSITY 发明人 LE JUNMING;VILCEK JAN T.;DADDONA PETER E.;GHRAYEB JOHN;KNIGHT DAVID M.;SIEGEL SCOTT A.;SHEALY DAVID J.
分类号 A61K39/395;C07K16/24;C07K16/30;(IPC1-7):A61K39/395 主分类号 A61K39/395
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