发明名称 Methods and compositions using stearoyl-CoA desaturase to identify triglyceride reducing therapeutic agents
摘要 The use of screening assays based on the role of human stearoyl-CoA desaturase-1 ("hSCD1") in human diseases, disorders or conditions relating to serum levels of triglyceride, VLDL, HDL, LDL, total cholesterol, or production of secretions from mucous membranes, monounsaturated fatty acids, wax esters, and the like, is disclosed. Also disclosed are conventions useful in the prevention and/or treatment of such diseases.
申请公布号 US2005250160(A1) 申请公布日期 2005.11.10
申请号 US20050178866 申请日期 2005.07.11
申请人 HAYDEN MICHAEL R;BROWNLIE ALISON J;NTAMBI JAMES M;MIYAZAKI MAKOTO;GRAY-KELLER MARK P;ATTIE ALAN D 发明人 HAYDEN MICHAEL R.;BROWNLIE ALISON J.;NTAMBI JAMES M.;MIYAZAKI MAKOTO;GRAY-KELLER MARK P.;ATTIE ALAN D.
分类号 G01N33/50;A61K31/00;A61K31/201;A61K31/426;A61K31/4439;A61K45/00;A61K48/00;A61P3/06;A61P3/10;A61P9/10;A61P43/00;C07K16/40;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N9/00;C12N9/02;C12N15/09;C12N15/113;C12Q1/02;C12Q1/25;C12Q1/26;C12Q1/68;G01N33/15;(IPC1-7):G01N33/53 主分类号 G01N33/50
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