Laser perforator

摘要

The present invention provides methods of introducing a substance into a living body by forming a plurality of areas on the stratum corneum of the skin such that each area has an enhanced permeability through to the capillary layer. A single laser beam is generated to irradiate the areas on the skin with subablative laser energy to perforate the skin to specific depths without substantially ablating the skin. The substance is introduced into the body by bringing the substance in contact with the areas of enhanced permeability. The present invention further provides lasers comprising a crystal with a partial matte surface-mirror element in combination with a beam splitter to generate a plurality of laser beams substantially concurrently from the single laser beam or with an acousto-optical modulator to sequentially deflect the single laser beam at a plurality of angles.