发明名称 |
COMPOSITIONS FOR DIAGNOSIS AND THERAPY OF DISEASES ASSOCIATED WITH ABERRANT EXPRESSION OF FUTRINS (R-SPONDINS) AND/OR WNT |
摘要 |
The present invention relates to a composition useful for the diagnosis of diseases associated with aberrant expression of the genes encoding the secreted proteins Futrin 1, 2, 3 and/or 4(= R-Spondin 2, 3, 1 and 4, respectively), e.g. in connection with tumors or diseases of the muscle, kidneys or bones. The present invention also relates to a pharmaceutical composition containing a compound which is capable of modifying (a) the expression of the gene encoding Futrin 1, 2, 3 and/or 4 or (b) the activity of the Futrin 1, 2, 3 and/or 4 protein. |
申请公布号 |
WO2005040418(A3) |
申请公布日期 |
2005.11.10 |
申请号 |
WO2004EP11269 |
申请日期 |
2004.10.08 |
申请人 |
DEUTSCHES KREBSFORSCHUNGSZENTRUM;NIEHRS, CHRISTOF;WU, WEI;GLINKA, ANDREI;KAZANSKAYA, OLGA |
发明人 |
NIEHRS, CHRISTOF;WU, WEI;GLINKA, ANDREI;KAZANSKAYA, OLGA |
分类号 |
A61K39/00;C07K14/47;C07K14/78;C12Q1/68 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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