发明名称 PROCESS (II) FOR THE PREPARATION OF POWDERED MEDICAMENT
摘要 According to the invention there is provided a method of treatment of a fine ly divided powdered medicament having a particle size smaller than 10 .mu.m and poor flowing properties to form, in a controlled m anner, agglomerates or pellets which are free flowing an d which are capable of breaking down to provide the finely divided medicament, compr ising the steps of agglomerating the powdered medicamen t having a particle size being smaller than 10 .mu.m by feeding the material t o a sieve, causing the finely divided powdered medicamen t to pass through the apertures of the sieve thereby obtaining agglomerates, spheroniz ing the resulting agglomerates in order to provide aggl omerates which are more spherical, more dense and more compact than the agglomerates resulting from the agglomeration process in the sieve, and sizing the agglomerates to obtain a uniform size of the final product. Acco rding to the invention there is also provided an apparat us for carrying out the method.
申请公布号 CA2172055(C) 申请公布日期 2005.11.08
申请号 CA19942172055 申请日期 1994.09.29
申请人 ASTRA AKTIEBOLAG 发明人 TROFAST, EVA;OLSSON, MAGNUS;AHLNECK, CLAES
分类号 A61J3/06;A61K9/16;B01J2/00;B01J2/20;(IPC1-7):A61J3/02;A61K9/72 主分类号 A61J3/06
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