发明名称 |
Methods and compositions relating to a cardiac-specific nuclear regulatory factor |
摘要 |
The present invention relates to a novel cardiac-specific transcription factor, myocardin. This molecule modulates the development and differentiation of cardiomyocytes and is a potent inhibitor of cell growth. Methods to exploit these observations are provided and include respecifiying non-cardiac cells into cardiac cells, stimulating cardiac tissue regeneration, and methods for treating cardiomyopathies, myocardial infarction.
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申请公布号 |
US6962798(B2) |
申请公布日期 |
2005.11.08 |
申请号 |
US20010029217 |
申请日期 |
2001.12.21 |
申请人 |
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM |
发明人 |
OLSON ERIC N.;WANG DA-ZHI |
分类号 |
A61K38/00;C07K14/47;C12N5/077;(IPC1-7):C12P21/02;C12N15/63;C12N1/21;C12N1/19;C07H21/04 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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