发明名称 |
Application of glucose transport mutants for production of aromatic pathway compounds |
摘要 |
This invention describes methods for enhancing carbon flow into a pathway of a host cell to enhance the biosynthetic production of compounds therefrom, the host cells being selected based on being phenotypically Pts<SUP>-</SUP>/glucose<SUP>+</SUP>. Such host cells are capable of transporting glucose without consuming PEP, resulting in conservation of PEP which can be re-directed into the pathway in order to enhance the production of desired compounds along the pathway. Pts<SUP>-</SUP>/glucose<SUP>+</SUP> mutants have been shown to be advantageous for the enhanced production of the aromatic amino acids.
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申请公布号 |
US6962794(B2) |
申请公布日期 |
2005.11.08 |
申请号 |
US19970940692 |
申请日期 |
1997.09.30 |
申请人 |
UNIVERSIDAD NACIONAL AUTONOMA DE MEXICO |
发明人 |
VALLE FERNANDO;MEJIA NOEMI;BERRY ALAN |
分类号 |
C12N1/20;C12N1/21;C12N15/52;C12P1/00;C12P13/22;C12P19/04;(IPC1-7):C12N1/00;C12N15/01;C12N15/09 |
主分类号 |
C12N1/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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