摘要 |
The invention provides a method for determining whether a subject is at risk of undergoing an infarction related to atherosclerosis comprising measuring an inflammation parameter in a sample obtained from said subject and determining whether the value of said inflammation parameter is indicative for said risk. Said sample preferably comprises a whole blood sample. More preferably, said inflammation parameter comprises an inflammation parameter of a cell and/or derivative thereof present in said sample, such as the amount of protein and/or RNA present upon and/or within such cells/derivatives. Additionally, an excreted product produced by said cell/derivative may be measured. The invention furthermore provides a method for quantifying at least one target nucleic acid in a sample, comprising incubating said sample with at least one probe capable of annealing to said target nucleic acid, amplifying annealed probes and quantifying said probes, characterized in that said sample comprises a whole blood sample. |
申请人 |
ACADEMISCH ZIEKENHUIS BIJ DE UNIVERSITEIT VAN AMSTERDAM;LEIDS UNIVERSITAIR MEDISCH CENTRUM;REITSMA, PIETER, HENDRIK;ROSENDAAL, FRITS, RICHARD |
发明人 |
REITSMA, PIETER, HENDRIK;ROSENDAAL, FRITS, RICHARD |