ПРИМЕНЕНИЕ ГИДРОХЛОРИДА 1-ФЕНИЛ-1-(1`-МЕТИЛЦИКЛОПЕНТИЛ)-4-ПИПЕРИДИНО-2-БУТИН-1-ОЛА, В КАЧЕСТВЕ СРЕДСТВА, ОБЛАДАЮЩЕГО М1 ХОЛИНОБЛОКИРУЮЩЕЙ АКТИВНОСТЬЮ

摘要

FIELD: organic chemistry, medicine, chemical-pharmaceutical industry, pharmacy. ^ SUBSTANCE: invention relates to a new agent with expressed selective activity with respect to central muscarinic acetylcholine receptors belonging to subtype M1. Agent represents 1-phenyl-1-(1'-methylcyclopentyl)-4-piperidino-2-butyne-1-ol hydrochloride of the formula (1) known early as low toxic cholinolytic. Agent expands a set of ligands used in research of mechanisms of the central nervous system function. Agent shows high capacity for penetration through blood-brain barrier, low toxicity and high effectiveness. ^ EFFECT: valuable medicinal properties of agent. ^ 1 tbl