| 发明名称 |
SYNERGISTIC ATTENUTATION OF VESICULAR STOMATITIS VIRUS, VECTORS THEREOF AND IMMUNOGENIC COMPOSITIONS THEREOF |
| 摘要 |
<p>The present invention broadly relates to the synergistic attenuation of vesicular stornatitis virus (VSV). More particularly, the invention relates to the identification of combined mutation classes which synergistically attenuate the pathogenicitnof VSV vectors in mammals and imrPWnogenic compositions thereof.</p> |
| 申请公布号 |
CA2561245(A1) |
申请公布日期 |
2005.10.20 |
| 申请号 |
CA20052561245 |
申请日期 |
2005.04.05 |
| 申请人 |
WYETH |
发明人 |
PARKS, CHRISTOPHER LEE;UDEM, STEPHEN A.;HENDRY, ROGER MICHAEL;CLARKE, DAVID KIRKWOOD |
| 分类号 |
C12N15/86;C07K14/145;C12N7/04 |
主分类号 |
C12N15/86 |
| 代理机构 |
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