发明名称 6-O-sulfated N-acetylheparosan and hematopoietic stem cell growth auxiliary agent
摘要 A 6-O-sulfated N-acetylheparosan in which a primary hydroxyl group of N-acetylglucosamine constituting N-acetylheparosan is sulfated; a hematopoietic stem cell growth auxiliary agent, which has hematopoietic stem cell growth-accelerating activity and comprises the 6-O-sulfated-N-acetylheparosan as an active ingredient; a medium for a hematopoietic stem cell, which comprises the hematopoietic stem cell growth auxiliary agent and an other medium component necessary for culturing the hematopoietic stem cell; a method for culturing a hematopoietic stem cell, which comprises culturing the hematopoietic stem cell in the presence of the hematopoietic stem cell growth auxiliary agent or in the medium for a hematopoietic stem cell; and a method for treating a blood disease, which comprises transplanting a hematopoietic stem cell cultured by the above method to bone marrow of a mammal.
申请公布号 US2005233453(A1) 申请公布日期 2005.10.20
申请号 US20050098417 申请日期 2005.04.05
申请人 SEIKAGAKU CORPORATION 发明人 KARIYA YUTAKA;KYOGASHIMA MAMORU;SUZUKI KIYOSHI;YASUDA YOUSUKE
分类号 A61K35/12;A61K35/28;A61P7/00;A61P35/02;C08B37/00;C08B37/10;C12N5/07;C12N5/074;C12N5/0775;C12N5/0789;(IPC1-7):C12N5/08 主分类号 A61K35/12
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