| 发明名称 |
Use of alpha-tubulin acetylation levels as a biomarker for protein deacetylase inhibitors |
| 摘要 |
The invention relates to a novel method for evaluating the antiproliferative activity of protein deacetylase inhibiting compounds and microtubule interacting agents, as well as a method for screening for compounds that inhibit cell growth or growth of tumors. The invention additionally provides a method for monitoring the progress of treatment against cellular growth or the growth of tumors.
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| 申请公布号 |
US2005227300(A1) |
申请公布日期 |
2005.10.13 |
| 申请号 |
US20050497333 |
申请日期 |
2005.05.19 |
| 申请人 |
ATADJA PETER W;HOVING SJOUKE;TOWBIN HARRY;WALKER HEATHER B;WARTMANN MARKUS;YELESWARAPU LAKSHMI |
发明人 |
ATADJA PETER W.;HOVING SJOUKE;TOWBIN HARRY;WALKER HEATHER B.;WARTMANN MARKUS;YELESWARAPU LAKSHMI |
| 分类号 |
A61K49/00;C12Q1/02;C12Q1/48;C12R1/91;G01N27/447;G01N33/15;G01N33/50;G01N33/574;(IPC1-7):G01N33/574 |
主分类号 |
A61K49/00 |
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