发明名称 |
Fluorescent labeled nucleotide derivatives |
摘要 |
Fluorescent labeled reporter compounds having a modified cyanine dye that is coupled to a nucleotide derivative through a linker are disclosed. The compounds are useful for nucleic acid sequence analysis. The fluorescent labeled reporter compounds are ring-locked cyanine dyes that are coupled to a nucleotide derivative, such as a modified DNA base, through a linker. These fluorescent labeled reporter compounds can be used as DNA chain-terminators in DNA synthesis to generate DNA fragments that are fluorescently-labeled at the 3'-terminal end of the DNA fragment.
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申请公布号 |
US2005227240(A1) |
申请公布日期 |
2005.10.13 |
申请号 |
US20040821500 |
申请日期 |
2004.04.09 |
申请人 |
SHEN GENE G;LIN YUAN;MICHAEL JOSEPHINE M |
发明人 |
SHEN GENE G.;LIN YUAN;MICHAEL JOSEPHINE M. |
分类号 |
C09B23/01;C09B23/08;C09B23/12;C12Q1/68;G01N21/64;G01N33/58;(IPC1-7):C12Q1/68;C07H21/04;C07D43/02 |
主分类号 |
C09B23/01 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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