发明名称 |
Antileishmanial dinitroaniline sulfanomides with activity against parasite tubulin |
摘要 |
Dinitroaniline compounds useful for the treatment of diseases caused by parasitic protozoa in subjects in need of such treatment. The compounds are particularly useful in the treatment of leishmaniasis. The compounds are preferably less cytotoxic to normal cells than oryzalin. Also provided are methods of treating subjects having diseases caused by parasitic protozoa, preferably humans. The method comprising administering a therapeutically effective amount of a dinitroaniline compound of the present invention to a subject in need of such treatment.
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申请公布号 |
US2005227982(A1) |
申请公布日期 |
2005.10.13 |
申请号 |
US20040512335 |
申请日期 |
2004.10.20 |
申请人 |
WERBOVETZ KARL;SACKETT DAN L;SALEM MANAR M |
发明人 |
WERBOVETZ KARL;SACKETT DAN L.;SALEM MANAR M. |
分类号 |
A61K31/135;A61K31/40;A61K31/537;C07C211/52;C07C237/30;C07C311/39;C07C311/44;C07D207/46;C07D265/30;C07D295/096;(IPC1-7):A61K31/537 |
主分类号 |
A61K31/135 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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