New heterocyclic amino compounds, their salts and a process for the preparation thereof

摘要

Novel compounds of the Formula (I) and acid addition salts thereof, wherein A represents an oxygen or sulphur atom and R represents a hydrogen atom or a straight or branched C1- 3 alkyl group, are prepared by reacting an appropriate furyl- or thienyl-2- or 3-carboxaldehyde with a dextrorotatory, laevoroatatory or racemic 1 - phenyl - 2 - aminopropane to give an imine of the Formula (III), reducing the imino group of the latter compound and, if desired, alkylating the resulting secondary amine with an aliphatic aldehyde and formic acid or with a halide of the formula R-X where X represents a halogen atom. Therapeutic compositions with anorexigenic properties, in forms suitable for oral or parenteral application, comprise compounds of the formula (I) and acid addition salts thereof, together with a suitable carrier therefor. or