A3 RECEPTOR-MEDIATED CARDIOPROTECTIVE PROTEINS AND THERAPEUTIC AND DIAGNOSTIC METHODS OF USE

摘要

Proteins are identified that exhibit an altered expression in mammalian cardiac tissue in response to A3 agonist infusion. These proteins are termed A3 receptor-mediated cardioprotective proteins (A3Ps) and protein isoforms (A3PIs) and are useful as pharmaceuticals and as targets in screening methods for identifying an agent capable of modulating the expression of one or more A3P and/or A3PI.