发明名称 STABLE INJECTABLE DICLOFENAC COMPOSITIONS
摘要 This invention relates to stable parenteral aqueous solutions comprising either (a) diclofenac or a pharmaceutically acceptable diclofenac salt and a cyclodextrin, or (b) an inclusion complex of diclofenac or a pharmaceuticall y acceptable diclofenac salt and a cyclodextrin, or a mixture of (a) and (b), which are suitable for intramuscular and intravenous administration. The solutions contain diclofenac or diclofenac salt, cyclodextrin, and an antioxidant selected from monothioglycerol, or a combination of ethylene diamine tetra-acetic acid and N-acetyl-cysteine.
申请公布号 CA2555429(A1) 申请公布日期 2005.10.06
申请号 CA20042555429 申请日期 2004.11.30
申请人 SHIMODA BIOTECH (PTY) LTD. 发明人 PENKLER, LAWRENCE JOHN
分类号 A61K47/18;A61K9/00;A61K31/195;A61K31/196;A61K31/724;A61K47/20;A61K47/40;A61K47/48;A61P29/00 主分类号 A61K47/18
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