Thiadiazole-amine compounds for the treatment of neurodegenerative disorders

摘要

The present invention relates to compounds of the Formula I wherein R¹, R³, R⁵, R⁷, X, Y and U are as defined. Compounds of the Formula I have activity inhibiting production of Abeta-peptide. The invention also relates to pharmaceutical compositions and methods of treating diseases and disorders, for example, neurodegenerative and/or neurological disorders, e.g., Alzheimer's disease, in a mammal comprising compounds of the Formula I.