CONTROL OF FEEDING BEHAVIOR BY CHANGING NEURONAL ENERGY BALANCE
摘要
Obesity is a worldwide health issue, affecting children and adults in developed and developing countries. Obesity is a disorder of both energy metabolism and appetite regulation, and may be understood as a dysfunction o f energy balance. Applicants have found a means for regulating food intake by a subject by administering a compound to the subject which affects neuronal energy balance. Applicants have found a means for regulating food intake by a subject administering a compound to the subject which targets the activity o f AMPK, in particular inhibiting activation, in particular hypothalamic. Applicants have also found a method of inducing weight loss in a subject by decreasing the subjects appetite by administering a compound to the subject which increases the subject's neuronal energy balance.
申请公布号
CA2560035(A1)
申请公布日期
2005.09.29
申请号
CA20052560035
申请日期
2005.03.18
申请人
FASGEN, LLC;THE JOHNS HOPKINS UNIVERSITY
发明人
KUHAJDA, FRANCIS P.;THUPARI, JAGAN N.;LANDREE, LESLIE E.;KIM, EUN-KYOUNG;MORAN, TIMOTHY H.;RONNETT, GABRIELLE V.