This invention discloses a novel method for the conversion of carboxylic acids to carbothioic acids and application of the method to the preparation of androstane carbothiolates, such as fluticasone propionate, which avoids column chromatography.
申请公布号
DE60105555(T2)
申请公布日期
2005.09.29
申请号
DE2001605555T
申请日期
2001.02.23
申请人
ABBOTT LABORATORIES, ABBOTT PARK
发明人
BARKALOW, JUFANG;CHAMBERLIN, A.;COOPER, J.;HOSSAIN, AZAD;HUFNAGEL, J.;LANGRIDGE, C.
