发明名称 |
Enhancement of anti-androgenic activity by a combination of inhibitors targeting different steps of a steroid-dependent gene activation pathway and uses thereof |
摘要 |
The present invention includes novel methods and compositions for inhibiting or reducing steroid-dependent gene activation including the administration of at least two compounds that act different steps within a steroid receptor gene activation pathway. Preferred methods may include administering a first compound able to induce degradation of a steroid receptor and administering a second compound able to inhibit gene activation at a different step of the steroid receptor pathway. Steroid-dependent gene activation may be reduced or inhibited, modulated or controlled greater when the at least two of the compounds are administered in combination or together.
|
申请公布号 |
US2005209205(A1) |
申请公布日期 |
2005.09.22 |
申请号 |
US20050045181 |
申请日期 |
2005.01.27 |
申请人 |
SHIH CHARLES;SU CHING-YUAN |
发明人 |
SHIH CHARLES;SU CHING-YUAN |
分类号 |
A61K31/12;A61K31/56;(IPC1-7):A61K31/56 |
主分类号 |
A61K31/12 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|