发明名称 |
GENETICALLY PROFILED CELL LINES (GPCL) AND METHODS OF UTILIZING SAME FOR GENETIC DISSECTION OF CELLULAR PHENOTYPES |
摘要 |
Genetically profiled cell cultures are provided along with a dataset representing the genetic profile of the cells. Also provided are methods and kits using same for the identification of the genetic basis of a trait, a disease or a state which can be directly or indirectly measured in a cell-based assay. In addition, the methods provided by the present invention can be used to: (i) identify novel drugs for the treatment and/or prevention of diseases (ii) determine population variation to drug responsiveness, efficacy, toxicity and adverse effects, and (iii) to optimize the drug lead process. |
申请公布号 |
WO2005068657(A3) |
申请公布日期 |
2005.09.22 |
申请号 |
WO2005IL00077 |
申请日期 |
2005.01.20 |
申请人 |
YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW;DARVASI, ARIEL;SHIFMAN, SAGIV |
发明人 |
DARVASI, ARIEL;SHIFMAN, SAGIV |
分类号 |
C12Q1/68 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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